Quality of Life of Patients with Stable Coronary Artery Disease Combined with Non-Alcoholic Fatty Liver Disease

Quality of life assessment is an integral part of a comprehensive treatment in modern medical practice. Analysis of quality of life of patients with comorbidities is an interesting and poorly understood issue. The objective of the research was to evaluate the quality of life of patients with postinf...

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Main Authors: Vakalyuk, Iryna (Author), Virstyuk, Nataliya (Author), Petryna, Vitaliy (Author)
Format: EJournal Article
Published: Ivano-Frankivsk National Medical University, 2016-12-02.
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001 galician_E2016416_646
042 |a dc 
100 1 0 |a Vakalyuk, Iryna  |e author 
700 1 0 |a Virstyuk, Nataliya  |e author 
700 1 0 |a Petryna, Vitaliy  |e author 
245 0 0 |a Quality of Life of Patients with Stable Coronary Artery Disease Combined with Non-Alcoholic Fatty Liver Disease 
260 |b Ivano-Frankivsk National Medical University,   |c 2016-12-02. 
500 |a https://ifnmujournal.com/gmj/article/view/E2016416 
520 |a Quality of life assessment is an integral part of a comprehensive treatment in modern medical practice. Analysis of quality of life of patients with comorbidities is an interesting and poorly understood issue. The objective of the research was to evaluate the quality of life of patients with postinfarction cardiosclerosis depending on the presence and progression of non-alcoholic fatty liver disease (NAFLD).Material and methods. The research included 300 patients with stable coronary artery disease (CAD). They included 160 patients without NAFLD (Group I) and 140 patients with NAFLD (Group II). 89 patients of Group II suffered from non-alcoholic liver disease (NALD) and 51 patients from non-alcoholic steatohepatitis (NASH). The control group consisted of 20 apparently healthy individuals. SF-36 and MacNew questionnaires were used to assess the quality of life. Results. The overall estimate according to SF-36 questionnaire detected a significant decrease in the patient's quality of life due to their low physical activity, mental ill-being, limitation of daily activities, significant effect of pain and low assessment of their health. Decrease in the quality of life was clearly dependent on NAFLD stage and was the lowest in case of NASH. The overall estimate of quality of life according to MacNew questionnaire was 1.5 times lower in patients of Group I compared to the control group, decreased almost by 1.4 times in patients with NALD compared to Group I and was 1.5 times lower in case of NASH compared to the patients with NALD (p<0.05). Conclusions. Patients with stable CAD combined with NAFLD were characterized by decrease in quality of life due to its physical, psycho-emotional and social components. Quality of life of patients with postinfarction cardiosclerosis depended on NAFLD progression and was the lowest in case of NASH. 
540 |a Copyright (c) 2017 Iryna Vakalyuk, Nataliya Virstyuk, Vitaliy Petryna 
540 |a https://creativecommons.org/licenses/by-nc/4.0 
546 |a eng 
690 |a quality of life 
690 |a postinfarction cardiosclerosis 
690 |a non-alcoholic fatty liver disease 
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
786 0 |n Galician Medical Journal; Vol. 23 No. 4 (2016); E2016416 
786 0 |n Galician Medical Journal; Том 23 № 4 (2016); E2016416 
786 0 |n 2414-1518 
787 0 |n https://ifnmujournal.com/gmj/article/view/E2016416/645 
787 0 |n https://ifnmujournal.com/gmj/article/view/E2016416/646 
856 4 1 |u https://ifnmujournal.com/gmj/article/view/E2016416/645  |z Get Fulltext 
856 4 1 |u https://ifnmujournal.com/gmj/article/view/E2016416/646  |z Get Fulltext