Microarray Image Analysis Using Genetic Algorithm

Microarray technology allows the simultaneous monitoring of thousands of genes. Based on the gene expression measurements, microarray technology have proven powerful in gene expression profiling for discovering new types of diseases and for predicting the type of a disease. Gridding, segmentation an...

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Main Authors: Sivalakshmi, Bolem (Author), Malleswara Rao, N. Naga (Author)
Format: EJournal Article
Published: Institute of Advanced Engineering and Science, 2016-12-01.
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042 |a dc 
100 1 0 |a Sivalakshmi, Bolem  |e author 
700 1 0 |a Malleswara Rao, N. Naga  |e author 
245 0 0 |a Microarray Image Analysis Using Genetic Algorithm 
260 |b Institute of Advanced Engineering and Science,   |c 2016-12-01. 
500 |a https://ijeecs.iaescore.com/index.php/IJEECS/article/view/6001 
520 |a Microarray technology allows the simultaneous monitoring of thousands of genes. Based on the gene expression measurements, microarray technology have proven powerful in gene expression profiling for discovering new types of diseases and for predicting the type of a disease. Gridding, segmentation and intensity extraction are the three important steps in microarray image analysis. This paper presents microarray image analysis using Genetic Algorithm. A new algorithm for microarray image contrast enhancement is presented using Genetic Algorithm. Contrast enhancement is crucial step in extracting edge information in image and finally this edge information is used in gridding of microarray image. Mostly segmentation of microarray image is carried out using clustering algorithms. Clustering algorithms have an advantage that they are not restricted to a particular shape and size for the spots. In this paper, segmentation using Genetic Algorithm by optimizing K-means index and Jm measure is presented. The qualitative analysis shows that the proposed method achieves better segmentation results than K-means and FCM algorithms. 
540 |a Copyright (c) 2016 Indonesian Journal of Electrical Engineering and Computer Science 
540 |a http://creativecommons.org/licenses/by-nc-nd/4.0 
546 |a eng 
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
655 7 |2 local 
786 0 |n Indonesian Journal of Electrical Engineering and Computer Science; Vol 4, No 3: December 2016; 561-567 
786 0 |n 2502-4760 
786 0 |n 2502-4752 
786 0 |n 10.11591/ijeecs.v4.i3 
787 0 |n https://ijeecs.iaescore.com/index.php/IJEECS/article/view/6001/5376 
856 4 1 |u https://ijeecs.iaescore.com/index.php/IJEECS/article/view/6001/5376  |z Get fulltext