The Role of Renin Angiotensin Aldosterone System in the Pathogenesis and Pathophysiology of COVID-19
The novel coronavirus also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whose origin is still having uncertainties related to the existence of an intermediate host, has created the currently ongoing pandemic of coronavirus disease 2019. (COVID-19) The binding assays of SARS-...
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IntechOpen,
2021-06-26.
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| LEADER | 01659 am a22001933u 4500 | ||
|---|---|---|---|
| 001 | intechopen_books_10488 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Sahin, Ozlem G. |e author |
| 245 | 0 | 0 | |a The Role of Renin Angiotensin Aldosterone System in the Pathogenesis and Pathophysiology of COVID-19 |
| 260 | |b IntechOpen, |c 2021-06-26. | ||
| 500 | |a https://mts.intechopen.com/articles/show/title/the-role-of-renin-angiotensin-aldosterone-system-in-the-pathogenesis-and-pathophysiology-of-covid-19 | ||
| 520 | |a The novel coronavirus also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) whose origin is still having uncertainties related to the existence of an intermediate host, has created the currently ongoing pandemic of coronavirus disease 2019. (COVID-19) The binding assays of SARS-CoV-2 spike protein receptor binding domain disclosed enhanced affinity with human angiotensin II-converting enzyme receptor (hACE2) comparing to the bat ACE2 receptors. ACE2, is an essential component of the regulatory mechanism of the renin-angiotensin-aldosterone system, (RAAS) and this pathway is considered to interact with the pathophysiology of COVID-19. In this chapter, we will discuss the key role of RAAS in the pathogenesis of SARS-CoV-2. | ||
| 540 | |a https://creativecommons.org/licenses/by/3.0/ | ||
| 546 | |a en | ||
| 690 | |a Renin-Angiotensin Aldosterone System | ||
| 655 | 7 | |a Chapter, Part Of Book |2 local | |
| 786 | 0 | |n https://www.intechopen.com/books/10488 | |
| 787 | 0 | |n ISBN:978-1-83968-286-5 | |
| 856 | \ | \ | |u https://mts.intechopen.com/articles/show/title/the-role-of-renin-angiotensin-aldosterone-system-in-the-pathogenesis-and-pathophysiology-of-covid-19 |z Get Online |