Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1

This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journe...

Full description

Saved in:
Bibliographic Details
Main Author: McKinley, Ryan Lucas (Author)
Format: Ebooks
Published: IntechOpen, 2022-01-19.
Subjects:
Online Access:Get Online
Tags: Add Tag
No Tags, Be the first to tag this record!
LEADER 02685 am a22001933u 4500
001 intechopen_books_10799
042 |a dc 
100 1 0 |a McKinley, Ryan Lucas  |e author 
245 0 0 |a Marijuana, a Journey through the Endocannabinoid System: Unmasking the Paradoxical Effect - Part 1 
260 |b IntechOpen,   |c 2022-01-19. 
500 |a https://mts.intechopen.com/articles/show/title/marijuana-a-journey-through-the-endocannabinoid-system-unmasking-the-paradoxical-effect-part-1 
520 |a This two-part section helps the reader to achieve a better understanding of how cannabis works as a viable medication for the endocannabinoid system (ECS) and central nervous system (CNS) in humans by identifying individual synergies between cannabinoids, or cannabinoids and terpenes in their journey through the ECS and CNS in various mammalian patient indicators to unmask this paradoxical effect. The specific biphasic/paradoxical manner in question was researched and inevitably identifies cannabis use that manipulates tryptophan uptake, serotonin release, and dopamine actuation. Therefore, a patient's diet may demand a higher tryptophan and dopa-L supplementation to avoid a paradoxical agitation on the receptor level. This chapter explains the pathology of how cannabis consistently reacts in the ECS for every individual, only separated by metabolism and disruption/trauma in the ECS and CNS, implying that there was no found paradoxical effect existing in cannabis, but in the patient, and thus is perceived the same in every individual, only mediated by metabolism, environment (surroundings), and the exception for individuals who process stimulants and tryptophan and/or serotonin in a disrupted manner causing a perceived paradoxical effect or the build-up to and/or what will be referred to as ASR/ATD. The cannabis industry, growers/breeders, interpeners/cannabis sommeliers/bud tenders, and dispensaries need to continue to constantly strive for more knowledge, just as the researchers and FDA need to continue their work to understand the benefits of cannabis, and most importantly, all must work together to remove cannabis from the Schedule I and Schedule 2 classification. 
540 |a https://creativecommons.org/licenses/by/3.0/ 
546 |a en 
690 |a Phenolic Compounds - Chemistry, Synthesis, Diversity, Non-Conventional Industrial, Pharmaceutical and Therapeutic Applications 
655 7 |a Chapter, Part Of Book  |2 local 
786 0 |n https://www.intechopen.com/books/10799 
787 0 |n ISBN:978-1-83969-346-5 
856 \ \ |u https://mts.intechopen.com/articles/show/title/marijuana-a-journey-through-the-endocannabinoid-system-unmasking-the-paradoxical-effect-part-1  |z Get Online