B Lymphocyte as a Target of Bacterial Infections

B lymphocytes are central players in the immune response; canonically, they have been recognized as precursors of antibody-producing cells: plasma cells. Recent findings have shown that the role of B lymphocytes goes far beyond the production of antibodies. There are different subtypes of B lymphocy...

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Main Authors: Castañeda-Sánchez, Jorge Ismael (Author), Duarte, Ana Rosa Muñoz (Author), Domínguez-López, María Lilia (Author), de la Cruz-López, Juan José (Author), Luna-Herrera, Julieta (Author)
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Published: IntechOpen, 2017-07-12.
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042 |a dc 
100 1 0 |a Castañeda-Sánchez, Jorge Ismael  |e author 
700 1 0 |a Duarte, Ana Rosa Muñoz  |e author 
700 1 0 |a Domínguez-López, María Lilia  |e author 
700 1 0 |a de la Cruz-López, Juan José  |e author 
700 1 0 |a Luna-Herrera, Julieta  |e author 
245 0 0 |a B Lymphocyte as a Target of Bacterial Infections 
260 |b IntechOpen,   |c 2017-07-12. 
500 |a https://mts.intechopen.com/articles/show/title/b-lymphocyte-as-a-target-of-bacterial-infections 
520 |a B lymphocytes are central players in the immune response; canonically, they have been recognized as precursors of antibody-producing cells: plasma cells. Recent findings have shown that the role of B lymphocytes goes far beyond the production of antibodies. There are different subtypes of B lymphocytes with different participations in innate and adaptive responses that include the recognition of the antigen, its processing, and its presentation to T lymphocytes, as well as the production of cytokines that impact and modulate the response toward the pathogen. Traditionally, it has been considered that B lymphocytes do not have phagocytic abilities that allow them to internalize, to process, or even to be infected by bacterial pathogens. The new information has shown that B lymphocytes can be readily infected by bacterial pathogens like Salmonella, Francisella, Moraxella, and Mycobacterium, among others, and respond to those infections. Some of the recent advances on these topics will be presented in this chapter. 
540 |a https://creativecommons.org/licenses/by/3.0/ 
546 |a en 
690 |a Lymphocyte Updates - Cancer, Autoimmunity and Infection 
655 7 |a Chapter, Part Of Book  |2 local 
786 0 |n https://www.intechopen.com/books/6004 
787 0 |n ISBN:978-953-51-3343-8 
856 \ \ |u https://mts.intechopen.com/articles/show/title/b-lymphocyte-as-a-target-of-bacterial-infections  |z Get Online