Chronic Pseudomonas aeruginosa Infection as the Pathogenesis of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD), resulted from tobacco smoking, has an extremely poor prognosis and is a major cause of chronic morbidity and mortality worldwide. In this chapter, we review the role of bacterial infection on the pathogenesis of COPD, with a particular focus on Pseudomon...

Full description

Saved in:
Bibliographic Details
Main Authors: Matsumoto, Takemasa (Author), Fujita, Masaki (Author)
Format: Ebooks
Published: IntechOpen, 2018-03-30.
Subjects:
Online Access:Get Online
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chronic obstructive pulmonary disease (COPD), resulted from tobacco smoking, has an extremely poor prognosis and is a major cause of chronic morbidity and mortality worldwide. In this chapter, we review the role of bacterial infection on the pathogenesis of COPD, with a particular focus on Pseudomonas aeruginosa. Chronic infection with P. aeruginosa has been shown to contribute to COPD pathogenesis under certain conditions. In addition, P. aeruginosa is a major factor influencing severe symptoms, acute exacerbation, and the progression of COPD. Treatment for chronic P. aeruginosa infection may become a new strategy for addressing COPD.
Item Description:https://mts.intechopen.com/articles/show/title/chronic-pseudomonas-aeruginosa-infection-as-the-pathogenesis-of-chronic-obstructive-pulmonary-diseas