Comparative Antibacterial Effects of a Novel Copper and Silver- Based Core/Shell Nanostructure by Sonochemical Method
In this study, the antibacterial effect of novel copper (Cu) and silver (Ag) metal-based core-shell nanostructures against Escherichia coli (E. coli-Gram negative) was investigated. The novel copper- and silver-based nanostructures were prepared separately by using nontoxic, biodegradable, and bioco...
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Main Authors: | , , , , |
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Format: | Ebooks |
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IntechOpen,
2018-11-05.
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Summary: | In this study, the antibacterial effect of novel copper (Cu) and silver (Ag) metal-based core-shell nanostructures against Escherichia coli (E. coli-Gram negative) was investigated. The novel copper- and silver-based nanostructures were prepared separately by using nontoxic, biodegradable, and biocompatible biopolymers chitosan and guar gum-polyvinyl alcohol (GG-PVA), which were modified by inorganic phases SiO2 and sepiolite. On the other hand, guar gum-PVA (GG-PVA) was modified by sepiolite, and this nanostructure was prepared only for silver. Besides, Cu was dispersed in a different biopolymer chitosan by sonochemical method in the presence and absence of SiO2. X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques were used to characterize the surface chemistry and morphology of the core/shell nanostructure. Nanoscale zero-valent Cu (NZVCu) was found under thin CuO film according to the XPS results. SEM images showed that spherical Cu/CuO@SiO2 nanostructures (∼100 nm) were homogenously dispersed in the chitosan by using sonochemical method. Antibacterial property of the core-shell nanostructures was analyzed by well-diffusion method against Escherichia coli (E. coli-Gram negative). Cu/CuO@SiO2 nanostructures were found very effective against the E. coli due to high ratio of NZVCu in the nanostructure. |
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Item Description: | https://mts.intechopen.com/articles/show/title/comparative-antibacterial-effects-of-a-novel-copper-and-silver-based-core-shell-nanostructure-by-son |