Synthesis of Tropane Derivatives
This chapter refers to tropane alkaloid compounds best known for their occurrence, biosynthesis, and pharmacological properties in a subsection of the plant family Solanaceae including the Atropa, Duboisia, Hyoscyamus, and Scopolia species, together with their semisynthetic derivatives. Tropane alka...
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2019-11-08.
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| LEADER | 01645 am a22001933u 4500 | ||
|---|---|---|---|
| 001 | intechopen_books_6828 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Alsamarrai, Abdulmajeed Salih Hamad |e author |
| 245 | 0 | 0 | |a Synthesis of Tropane Derivatives |
| 260 | |b IntechOpen, |c 2019-11-08. | ||
| 500 | |a https://mts.intechopen.com/articles/show/title/synthesis-of-tropane-derivatives | ||
| 520 | |a This chapter refers to tropane alkaloid compounds best known for their occurrence, biosynthesis, and pharmacological properties in a subsection of the plant family Solanaceae including the Atropa, Duboisia, Hyoscyamus, and Scopolia species, together with their semisynthetic derivatives. Tropane alkaloids are useful as parasympatholytics that competitively antagonize acetylcholine. The bicyclic ring of tropane moiety forms the base of these alkaloids, and the largest number of tropane alkaloids is substituted on the atom C-3 of the tropane ring in the form of ester derivatives. Also, this chapter provides routes to previous methods for synthesizing tropane-2-yl derivatives as well as new routes to synthesize 2-(p-toluenesulphonyl) tropane-2-ene (anhydroecgonine). The new strategy for synthesizing anhydroecgonine might be helpful to adopt the best method of synthesizing tropane-2-yl derivatives. | ||
| 540 | |a https://creativecommons.org/licenses/by/3.0/ | ||
| 546 | |a en | ||
| 690 | |a Alkaloids - Their Importance in Nature and Human Life | ||
| 655 | 7 | |a Chapter, Part Of Book |2 local | |
| 786 | 0 | |n https://www.intechopen.com/books/6828 | |
| 787 | 0 | |n ISBN:978-1-78984-576-1 | |
| 856 | \ | \ | |u https://mts.intechopen.com/articles/show/title/synthesis-of-tropane-derivatives |z Get Online |