Vitamin K2: A Vitamin that Works like a Hormone, Impinging on Gene Expression
Vitamin K2 binds to the intranuclear receptor SXR and results in the activation of a plethora of genes, both directly and indirectly. Among these genes are important biological markers of cellular characteristics or features (also known as cell phenotypes), as well as a set of molecules known to be...
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| LEADER | 01998 am a22001933u 4500 | ||
|---|---|---|---|
| 001 | intechopen_books_6883 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Gordeladze, Jan Oxholm |e author |
| 245 | 0 | 0 | |a Vitamin K2: A Vitamin that Works like a Hormone, Impinging on Gene Expression |
| 260 | |b IntechOpen, |c 2019-04-17. | ||
| 500 | |a https://mts.intechopen.com/articles/show/title/vitamin-k2-a-vitamin-that-works-like-a-hormone-impinging-on-gene-expression | ||
| 520 | |a Vitamin K2 binds to the intranuclear receptor SXR and results in the activation of a plethora of genes, both directly and indirectly. Among these genes are important biological markers of cellular characteristics or features (also known as cell phenotypes), as well as a set of molecules known to be involved in both hormone-induced, G-protein-mediated cell signalling, either directly or indirectly activating so-called sirtuins and/or histone deacetylaces (HDACs), known as determinants of cell types and their specific functions in a given tissue. Hence, vitamin K2 may be closely involved in or serving as a traditional molecular 'link' between hormonal receptors and intracellular signalling pathways. It has been stated that a true hormone is a product of living cells, which circulates in body fluids (such as blood) and elicits a specific and often stimulatory effect on the activity of cells situated remotely from its point of origin. A large bulk of evidence published over the past 10 years establishes vitamin K2 in this category of substances. Hence, vitamin K2 should be considered and consequently classified as a hormone. | ||
| 540 | |a https://creativecommons.org/licenses/by/3.0/ | ||
| 546 | |a en | ||
| 690 | |a Cell Signalling - Thermodynamics and Molecular Control | ||
| 655 | 7 | |a Chapter, Part Of Book |2 local | |
| 786 | 0 | |n https://www.intechopen.com/books/6883 | |
| 787 | 0 | |n ISBN:978-1-83880-065-9 | |
| 856 | \ | \ | |u https://mts.intechopen.com/articles/show/title/vitamin-k2-a-vitamin-that-works-like-a-hormone-impinging-on-gene-expression |z Get Online |