The BDNF Loop 4 Dipeptide Mimetic Bis(<em>N</em>-monosuccinyl-L-seryl-L-lysine)hexamethylenediamide Is Active in a Depression Model in Mice after Acute Oral Administration
Low-molecular mimetic BDNF GSB-106, which is a substituted dimeric dipeptide, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide, was designed and synthesized in the V. V. Zakusov Research Institute of Pharmacology. The dipeptide activates TrkB, PI3K/AKT, and MAPK/ ERK. GSB-106 is being devel...
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Main Authors: | Povarnina, Polina (Author), Firsova, Yulia N. (Author), Tallerova, Anna V. (Author), Mezhlumyan, Аrmen G. (Author), Kruglov, Sergey V. (Author), Antipova, Tatiana A. (Author), Gudasheva, Tatiana A. (Author), Seredenin, Sergey B. (Author) |
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Format: | Ebooks |
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IntechOpen,
2019-10-23.
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Online Access: | Get Online |
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