Passenger or Driver: Can Gene Expression Profiling Tell Us Anything about LINE-1 in Cancer?

LINE-1 retrotransposons are expressed in epithelial cancers but not normal adult tissues. Previously, we demonstrated repression of cell proliferation, migration, and invasion genes in L1-reverse transcriptase-inhibited T47D cells, while genes involved in cell projection, formation of vacuolar membr...

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Main Authors: Ohms, Stephen (Author), Dahlstrom, Jane E. (Author), Rangasamy, Danny (Author)
Format: Ebooks
Published: IntechOpen, 2018-02-28.
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