Aktivitas Antibakteri Ekstrak Etanol dan Etil Asetat Batang Tanaman Brotowali (Tinospora crispa, L. Miers) terhadap Bakteri Escherichia coli Enteropatogenik (EPEC) Penyebab Penyakit Diare

Diarrheal diseases is an endemic desease in Indonesia and potential desease of Kejadian Luar Biasa (KLB) which often leads to death. Enteropatogenic Escherichia coli (EPEC) is one of pathogenic bacteria which can cause diarrhea. Brotowali plant (Tinospora crispa, L. Miers) is one of traditional medi...

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Main Authors: Fathmah, Ema Nuzula (Author), Pujiyanto, Sri (Author), Raharjo, Budi (Author)
פורמט: EJournal Article
יצא לאור: Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro, 2019-07-20.
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042 |a dc 
100 1 0 |a Fathmah, Ema Nuzula  |e author 
100 1 0 |e contributor 
700 1 0 |a Pujiyanto, Sri  |e author 
700 1 0 |a Raharjo, Budi  |e author 
245 0 0 |a Aktivitas Antibakteri Ekstrak Etanol dan Etil Asetat Batang Tanaman Brotowali (Tinospora crispa, L. Miers) terhadap Bakteri Escherichia coli Enteropatogenik (EPEC) Penyebab Penyakit Diare 
260 |b Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro,   |c 2019-07-20. 
500 |a https://ejournal.undip.ac.id/index.php/bioma/article/view/24431 
520 |a Diarrheal diseases is an endemic desease in Indonesia and potential desease of Kejadian Luar Biasa (KLB) which often leads to death. Enteropatogenic Escherichia coli (EPEC) is one of pathogenic bacteria which can cause diarrhea. Brotowali plant (Tinospora crispa, L. Miers) is one of traditional medicinal plants which is widely used to treat various diseases and and relatively have no side effects than chemical drugs. he purpose of this research is to know the antibacterial activity of Brotowali (Tinospora crispa, L. Miers) stems ethanol and ethyl acetate extract in inhibiting the growth of EPEC bacteria causing diarrheal disease. Brotowali extract was obtained by maceration method using ethanol and ethyl acetate solvent. The condensed extract obtained was dissolved in DMSO 100% until the concentration of the extract to 20%; 40% and 60%. Test of antibacterial activity used diffusion method using paperdisk. The ethanol and ethyl acetate extract of brotowali stems were each tested on EPEC bacteria. The results in this study are the inhibition zone on ethanol and ethyl acetate extract stem of brotowali plant to EPEC bacteria. The antibacterial activity of brotowali stem ethanol extract at 60% concentration showed the best effect compared to the concentration of 20% and 40%. The antibacterial activity of ethyl acetate extract of brotowali stem was as good at concentration of 20%; 40% and 60%. The antibacterial activity of brotowali stem ethyl acetate extract showed better results than brotowali stem ethanol extract 
540 |a Copyright (c) 2019 Bioma : Berkala Ilmiah Biologi 
546 |a eng 
690
655 7 |a info:eu-repo/semantics/article  |2 local 
655 7 |a info:eu-repo/semantics/publishedVersion  |2 local 
655 7 |a Peer-reviewed Article  |2 local 
786 0 |n Bioma : Berkala Ilmiah Biologi; Vol. 21, No 1, Tahun 2019; 1-8 
786 0 |n 2598-2370 
786 0 |n 1410-8801 
787 0 |n https://ejournal.undip.ac.id/index.php/bioma/article/view/24431/15505 
856 4 1 |u https://ejournal.undip.ac.id/index.php/bioma/article/view/24431/15505  |z Get Fulltext