B-Vitamins and One-Carbon Metabolism
Folate, vitamin B12, vitamin B6 and riboflavin play a key role as coenzymes in one-carbon metabolism which, in turn, is essential for a broad range of fundamental physiological processes, including RNA and DNA synthesis, cell division, tissue growth and methylation. Deficiencies or imbalance of B-vi...
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MDPI - Multidisciplinary Digital Publishing Institute,
2018.
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| LEADER | 01977 am a22001813u 4500 | ||
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| 001 | oer_unej_101 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a PENTIEVA, Kristina |e author |
| 245 | 0 | 0 | |a B-Vitamins and One-Carbon Metabolism |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute, |c 2018. | ||
| 500 | |a http://oer.library.unej.ac.id//index.php?p=show_detail&id=101 | ||
| 500 | |a 579 | ||
| 520 | |a Folate, vitamin B12, vitamin B6 and riboflavin play a key role as coenzymes in one-carbon metabolism which, in turn, is essential for a broad range of fundamental physiological processes, including RNA and DNA synthesis, cell division, tissue growth and methylation. Deficiencies or imbalance of B-vitamins, as well as genetic polymorphisms and environmental factors, are shown to disturb the normal function of one-carbon metabolism with adverse effects on human health. Although a vast volume of research has already been conducted in this area, there are still significant gaps in our knowledge that require further investigation. This prompted the journal Nutrients to publish a Special Issue focused on the novel findings in the area of B-vitamins and one-carbon metabolism. The Special Issue published 26 research papers and reviews on various topics pertinent to one-carbon metabolism. Several of the published papers examined the relationship between folate and the metabolically related B-vitamins and degenerative diseases in ageing. Porter et al. provided an extensive review on the causes and consequences of low B-vitamin status and the risk for development of cardiovascular disease, cognitive dysfunction and osteoporosis. In a large cohort of French older adults, followed for approximately 10 years, Lefevre-Arbogast et al. demonstrated that higher intake of folate was associated with a decreased risk of dementi | ||
| 546 | |a en | ||
| 690 | |a Metabolism | ||
| 690 | |a 579 | ||
| 655 | 7 | |a Text |2 local | |
| 856 | 4 | 1 | |u http://oer.library.unej.ac.id//index.php?p=show_detail&id=101 |z Get Fulltext |