Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models
Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by chan...
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Springer,
2016.
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| LEADER | 01181 am a22001933u 4500 | ||
|---|---|---|---|
| 001 | oer_unej_1135 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Aslak Tveito |e author |
| 700 | 1 | 0 | |a Glenn T. Lines |e author |
| 245 | 0 | 0 | |a Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models |
| 260 | |b Springer, |c 2016. | ||
| 500 | |a http://oer.library.unej.ac.id//index.php?p=show_detail&id=1135 | ||
| 500 | |a 551 | ||
| 520 | |a Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize the use of numerical methods and provide sufficient details for the reader to implement the models and thereby study the effect of various drugs. | ||
| 546 | |||
| 690 | |a Geology | ||
| 690 | |a 551 | ||
| 655 | 7 | |a Text |2 local | |
| 856 | 4 | 1 | |u http://oer.library.unej.ac.id//index.php?p=show_detail&id=1135 |z Get Fulltext |