Natural Antibodies in Health and Disease
Natural antibodies (NAbs) are found in normalindividuals in the absence of exogenous antigenicstimulation. Natural antibodies rapidly recognizeand protect against pathogens that have not beenpreviously encountered. NAbs also cross-react withseveral self-antigens, which, besides their role as a first...
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| Format: | Ebooks |
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Frontiers Media SA,
2018.
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| Summary: | Natural antibodies (NAbs) are found in normalindividuals in the absence of exogenous antigenicstimulation. Natural antibodies rapidly recognizeand protect against pathogens that have not beenpreviously encountered. NAbs also cross-react withseveral self-antigens, which, besides their role as a first line of defense against pathogens, affords them theability to perform important housekeeping functionsin healthy organisms. Such housekeeping functionsinclude the clearance of oxidized damaged structuresand/or apoptotic cells, which prevents the inductionof pro-inflammatory effects. In addition, |
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| Item Description: | http://oer.library.unej.ac.id//index.php?p=show_detail&id=432 615 |