Calcium Signaling in Human Health and Diseases
Intracellular Ca2+ signals regulate a myriad of cellular functions, ranging from short-term responses, such as excitation-contraction coupling and stimulus-secretion coupling, to long-term processes, such as proliferation, gene expression, differentiation, motility, synaptic plasticity, programmed c...
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MDPI - Multidisciplinary Digital Publishing Institute,
2019.
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| 001 | oer_unej_496 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Francesco Moccia |q (Ed.) |e author |
| 245 | 0 | 0 | |a Calcium Signaling in Human Health and Diseases |
| 260 | |b MDPI - Multidisciplinary Digital Publishing Institute, |c 2019. | ||
| 500 | |a http://oer.library.unej.ac.id//index.php?p=show_detail&id=496 | ||
| 500 | |a 612 | ||
| 520 | |a Intracellular Ca2+ signals regulate a myriad of cellular functions, ranging from short-term responses, such as excitation-contraction coupling and stimulus-secretion coupling, to long-term processes, such as proliferation, gene expression, differentiation, motility, synaptic plasticity, programmed cell death (or apoptosis), and metabolism. It is, therefore, not surprising that any derangement of the multifaceted Ca2+ toolkit that shapes the elevation in intracellular Ca2+ concentration ([Ca2+]i) may lead to severe pathological disorders, including cancer, chronic heartfailure, epileptic and neurodegenerative disorders, immunodeficiency, and developmental defects.An increase in [Ca2+]i is shaped by the concerted interaction among the components of an extremelyversatile network of channels, transporters, pumps, and buffers that can be uniquely assembled byeach cell type to generate intracellular Ca2+ signals with spatio-temporal properties precisely tailoredto regulate specific functions. | ||
| 546 | |a en | ||
| 690 | |a Physiology | ||
| 690 | |a 612 | ||
| 655 | 7 | |a Text |2 local | |
| 856 | 4 | 1 | |u http://oer.library.unej.ac.id//index.php?p=show_detail&id=496 |z Get Fulltext |