Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer in Diltiazem Hydrochloride Mucoadhesive Buccal Film
Diltiazem hydrochloride (HCl) is a drug with low bioavailability due to the high rate of the first-pass metabolism and a short half-life of the drug (3-5h); hence, mucoadhesive buccal films were made to overcome this weakness. The bioavailability of Diltiazem HCl may increase if the buccal preparati...
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| Main Authors: | , , |
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| Format: | Academic Paper |
| Published: |
Indonesian Journal of Pharmacy,
2021-04-26T02:45:08Z.
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| Subjects: | |
| Online Access: | Get Fulltext |
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