The unfolded protein response in plants: A fundamental adaptive cellular response to internal and external stresses
Journal of Proteomics
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| Main Authors: | , , |
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| Format: | Academic Paper |
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2017-11-27T02:10:38Z.
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| Online Access: | Get Fulltext |
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| LEADER | 02145 am a22002893u 4500 | ||
|---|---|---|---|
| 001 | repository_unej_123456789_83361 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Fanata, Wahyu Indra Duwi |e author |
| 500 | |a 1874-3919 | ||
| 500 | |a http://repository.unej.ac.id/handle/123456789/83361 | ||
| 700 | 1 | 0 | |a Sang Yeol Lee |e author |
| 700 | 1 | 0 | |a Kyun Oh Lee |e author |
| 245 | 0 | 0 | |a The unfolded protein response in plants: A fundamental adaptive cellular response to internal and external stresses |
| 260 | |c 2017-11-27T02:10:38Z. | ||
| 520 | |a Journal of Proteomics | ||
| 520 | |a In eukaryotic cells, proteins that enter the secretory pathway are translated on membranebound ribosomes and translocated into the endoplasmic reticulum (ER), where they are subjected to chaperone-assisted folding, post-translational modification and assembly. During the evolution of the eukaryotic cell, a homeostatic mechanism was developed to maintain the functions of the ER in the face of various internal and external stresses. The most severe stresses imposed on eukaryotic cells can induce ER stress that can overwhelm the processing capacity of the ER, leading to the accumulation of unfolded proteins in the ER lumen. To cope with this accumulation of unfolded proteins, the unfolded protein response (UPR) is activated to alter transcriptional programs through inositol-requiring enzyme 1 (IRE1) and bZIP17/28 in plants. In addition to transcriptional induction of UPR genes, quality control (QC), translational attenuation, ER-associated degradation (ERAD) and ER stress-induced apoptosis are also conserved as fundamental adaptive cellular responses to ER stress in plants. This article is part of a Special Issue entitled: Translational Plant Proteomics. | ||
| 546 | |a en | ||
| 690 | |a Endoplasmic reticulum stress | ||
| 690 | |a Unfolded protein response | ||
| 690 | |a QUALITY CONTROL | ||
| 690 | |a Endoplasmic reticulum-associated | ||
| 690 | |a DEGRADATION | ||
| 690 | |a APOPTOSIS | ||
| 690 | |a PLANTS | ||
| 655 | 7 | |a Article |2 local | |
| 787 | 0 | |n http://repository.unej.ac.id/handle/123456789/83361 | |
| 856 | 4 | 1 | |u http://repository.unej.ac.id/handle/123456789/83361 |z Get Fulltext |