Ginger Extract and its Compound, 6-shogaol, Attenuates Painful Diabetic Neuropathy in Mice via Reducing TRPV1 and NMDAR2B Expressions in the Spinal Cord

Ethnopharmacological relevance: In silico data revealed that the active compound of ginger (Zingiber officinale Roscoe), 6-shogaol, has strong affinity toward transient receptor potential vanilloid-1 (TRPV-1). TRPV-1 is expressed in nervous tissue and pancreatic β-cells. Prolonged induction of TRPV-1 is...

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Bibliographic Details
Main Authors: FAJRIN, Fifteen Aprila (Author), NUGROHO, Agung Endro (Author), NURROCHMAD, Arief (Author), SUSILOWATI, Rina (Author)
Format: Academic Paper
Published: Journal of Ethnopharmacology, 249 (2020) 112396, 2020-06-05T03:33:43Z.
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