Evolution of NK-mediated target recognition under the pressure of physiologic or pathologic stimuli

Evolution of NK-mediated target recognition under the pressure of physiologic or pathologic stimuli

Since their discovery NK cells have come out as potential tools to fight cancer and viruses. This finding early urged different groups to study the mechanisms governing NK cell function. The identification of the MHC-I-specific inhibitory receptors (i.e. KIRs, NKG2A and certain Ly49 molecules) allow...

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Bibliographic Details
Main Author: Miguel Lopez-Botet (auth)
Other Authors: Simona Sivori (auth), Daniel Olive (auth), Massimo Vitale (auth)
Format: Book Chapter
Published: Frontiers Media SA 2015
Subjects:
ILC
innate immunity
KIR
Autoimmune Diseases
decidual NK cell
NCR
anti-viral immune responses
anti-tumor immunity
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