The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance

The Role of Aire, microRNAs and Cell-Cell Interactions on Thymic Architecture and Induction of Tolerance

The focus of this eBook is to bring new insights into central immune tolerance. To fulfill that, much has been discussed about the master in the regulation of tolerance, the autoimmune regulator (Aire) gene the main thymus cell type that expresses this gene, the medullary thymic epithelial cells (mT...

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Bibliographic Details
Main Author: Geraldo Aleixo Passos (auth)
Other Authors: Ernna Herida Oliveira (auth), Daniella Areas Mendes-da-Cruz (auth)
Format: Book Chapter
Published: Frontiers Media SA 2016
Subjects:
thymic crosstalk
Central Tolerance
promiscuous gene expression
Aire gene
cell-cell interaction
thymocyte
microRNA
Thymic B cell
Chemokines
Thymus
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