Structural and functional aspects of membranes : The involvement of lipid rafts in Alzheimer's disease pathogenesis. The interplay between protein oligomers and plasma membrane physicochemical features in determining cytotoxicity

Alzheimer's disease (AD) is a common form of dementia characterized by the formation of extracellular senile plaques composed of aggregated amyloid peptide (Aβ). The present studies provide evidence that: cell resistance to amyloid toxicity is related to lipid raft cholesterol content. Choleste...

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Main Author: Elisa Evangelisti (auth)
Format: Book Chapter
Published: Firenze University Press 2013
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