Systems Analytics and Integration of Big Omics Data

Systems Analytics and Integration of Big Omics Data

A "genotype"" is essentially an organism's full hereditary information which is obtained from its parents. A ""phenotype"" is an organism's actual observed physical and behavioral properties. These may include traits such as morphology, size, height, eye...

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Auteur principal: Hardiman, Gary (auth)
Format: Chapitre de livre
Publié: MDPI - Multidisciplinary Digital Publishing Institute 2020
Sujets:
precision medicine informatics
n/a
drug sensitivity
chromatin modification
cell lines
biocuration
neurodegeneration
multivariate analysis
artificial intelligence
epigenetics
missing data
sequencing
clinical data
class imbalance
integrative analytics
algorithm development for network integration
deep phenotype
non-omics data
feature selection
Gene Ontology
miRNA-gene expression networks
omics data
plot visualization
Alzheimer's disease
tissue classification
epidemiological data
proteomic analysis
genotype
RNA expression
indirect effect
multi-omics
dementia
multiomics integration
data integration
phenomics
network topology analysis
challenges
transcriptome
enrichment analysis
regulatory genomics
scalability
heterogeneous data
systemic lupus erythematosus
database
microtubule-associated protein tau
disease variants
genomics
joint modeling
distance correlation
annotation
phenotype
direct effect
curse of dimensionality
gene-environment interactions
logic forest
machine learning
KEGG pathways
multivariate causal mediation
amyloid-beta
bioinformatics pipelines
support vector machine
pharmacogenomics
candidate genes
tissue-specific expressed genes
cognitive impairment
causal inference
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