Tailoring NK Cell Receptor-Ligand Interactions: An Art in Evolution

Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is mediated by positive signals transduced by activating receptors upon engagement of ligands on target surface. These stimulatory pathways are counterbalanced by inhibitory receptors that raise NK cell activ...

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Bibliographic Details
Main Author: Gianfranco Pittari (auth)
Other Authors: Antoine Toubert (auth), Ulrike Koehl (auth)
Format: Book Chapter
Published: Frontiers Media SA 2018
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