Targeting PI3K/mTOR signaling in cancer

The phosphatidylinositol 3-kinase (PI3K)/mTOR pathway integrates signals from growth factors with nutrient signals and other conditions and controls multiple cell responses, including proliferation, survival and metabolism. Deregulation of the PI3K pathway has been extensively investigated in connec...

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Main Author: Alexandre Arcaro (auth)
Format: Book Chapter
Published: Frontiers Media SA 2014
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