Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics

Hypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are integral components of tumor microenvironment and conduce to metabolic adapta...

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Main Author: Christian R. Gomez (auth)
Format: Book Chapter
Published: Frontiers Media SA 2017
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