Tyrosine Kinases as Druggable Targets in Cancer

Protein tyrosine kinase (PTK) deregulation contributes to growth of cancer and many other diseases. The development of small-molecule tyrosine kinase inhibitors (TKIs) that target the deregulated PTKs, such as epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) and Bcr-ABL...

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Other Authors: Ren, Huan (Editor)
Format: Book Chapter
Published: IntechOpen 2019
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