Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits

Asthma : Current Perspectives on Phenotypes, Endotypes, and Treatable Traits

Asthma is a common complex and heterogeneous respiratory disease with an increasing prevalence in developed countries. Asthma is a disease consisting of different phenotypes that are driven by different mechanistic pathways (endotypes). The recognition of these phenotypes and endotypes is central to...

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Bibliographic Details
Other Authors: Rovina, Nikoletta (Editor)
Format: Book Chapter
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Medicine
asthma
lactic acidosis
hyperchloremic acidosis
hypocapnia
hypercapnia
wheezing
bronchial biopsies
symptom persistence
clinical remission
eosinophil
adhesion
viability
proliferation
airway smooth muscle cell
pulmonary fibroblast
phenotype
acute severe asthma exacerbation
near fatal asthma
severe asthma
inflammation
interleukin-5 (IL-5)
anti-IL-5
interleukin-4
airway remodeling
matrix metalloproteinases-9
tissue inhibitor of metalloproteinase-1
alveolar macrophages
lung function
bronchodilation
resistance
obstruction
reproducible
spirometry
obstructive sleep apnea
bronchial asthma
alternative overlap syndrome
exacerbation
reactive oxygen species
PBMC
mitochondrial function
innate immunity
immune regulation
NLRP3
IL-1β
allergic airway inflammation
microbiome
pathogenesis
immune responses
PreDicta
preschool
FeNO
asthma-specific quality of life
chronic rhinitis
disease-specific quality of life
health-related quality of Life (HRQLQ)
children
longitudinal study
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