New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies

New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies

The cancer stem cell (CSC) paradigm represents one of the most prominent breakthroughs of the last decades in tumor biology. CSCs are that subpopulation within a tumor that can survive conventional therapies and as a consequence are able to fuel tumor recurrence. Nevertheless, the biological charact...

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Bibliographic Details
Other Authors: Cavallaro, Ugo (Editor), Giordano, Marco (Editor)
Format: Book Chapter
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:
Research & information: general
Biology, life sciences
Cadherin 11
WNT signaling
β-catenin
cancer stem cells
TNBC
early breast cancer
bevacizumab
neoadjuvant chemotherapy
ALDH1
solid cancer
chemo-resistance
HDAC inhibitors
head and neck squamous cell carcinoma
SRC
dasatinib
saracatinib
EC-8042
Ovarian cancer
Wnt signaling
tumor progression
therapy resistance
exosomes
oral cancer risk
oral epithelial dysplasia
SOX2
immunohistochemistry
oral squamous cell carcinoma
genome-wide
transcriptome
lung cancer
ATAC-seq
RNA-seq
CSCs
NSCLC
B4GALT1
LUAD
breast cancer
lipid
metabolism
therapeutic resistance
bowel cancer
organoid
tumoroid
colorectal
colon
stem cell
chemotherapy resistance
ovarian cancer
cancer stem cell
genetic heterogeneity
SNP array
L1CAM
chemoresistance
epithelial-mesenchymal transition
cancer therapy
cell adhesion molecule
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