Ubiquitination in Health and Diseases

Ubiquitination in Health and Diseases

Ubiquitination is a biological process mediated by ubiquitin itself, the E1 ubiquitin-activating enzyme, E2 ubiquitin-conjugating enzyme, E3 ubiquitin ligase, and deubiquitinating enzyme, respectively. Currently, these multiple biological steps are revealed to participate in various life phenomena,...

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Dettagli Bibliografici
Altri autori: Ishigami, Tomoaki (Redattore)
Natura: Capitolo di libro
Pubblicazione: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Soggetti:
Humanities
Social interaction
deubiquitinase
degradation
therapeutic target
cancer
hematopoiesis
hematopoietic stem cells
immune response
regulation of gene expression
ubiquitin system
genetic diseases
ubiquitin ligase
deubiquitinases
monoubiquitin signaling
vesicular trafficking
protein complex formation
inflammation
inhibitor
innate immune
interferon
LUBAC
NF-κB
ubiquitin
Parkinson's disease
dopa-responsive dystonia
tyrosine hydroxylase
α-synuclein
fatty acid-binding protein 3
ubiquitination
proteasomal degradation
ubiquitin-proteasome system
mitochondria
E3 ubiquitin ligase
MITOL/MARCH5
salt-sensitive hypertension
Nedd4L/Nedd4-2
epithelial sodium channel
aldosterone sensitive distal nephron
excitation-transcription coupling
RNF183
RNF186
RNF182
RNF152
RING finger
mTOR
endoplasmic reticulum stress
osmotic stress
ubiquitin code
virus infection
virus-host interaction
tau protein
semisynthesis
disulfide-coupling
polyubiquitin
fibrils
aggregation
neurodegeneration
deubiquitination
inhibitors
protein quality control
proteolysis
protein stabilization
regulatory T cells
mesenchymal stem cell
cortical bone derived stem cell
myocardial infarction
blood pressure
renal salt reabsorption
vascular function
ubiquitin proteasome system
ubiquitin-proteasome pathway
cilia
ciliogenesis
differentiation
proliferation
ciliopathy
E3s
DUBs
UPS
neurodegenerative disease
immune-related diseases
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