Toxin-Antitoxin Systems in Pathogenic Bacteria

Toxin-Antitoxin Systems in Pathogenic Bacteria

Bacterial toxin-antitoxin (TA) systems, which are ubiquitously present in bacterial genomes, are not essential for normal cell proliferation. The TA systems regulate fundamental cellular processes, facilitate survival under stress conditions, have essential roles in virulence and represent potential...

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Detalhes bibliográficos
Outros Autores: Alonso, Juan Carlos (Editor)
Formato: Capítulo de Livro
Publicado em: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Assuntos:
Medicine
tuberculosis
toxin-antitoxin systems
bacterial cell death
NAD+
stress-response
toxin-antitoxin system
mazF
type II
toxin
mRNA interferase
X-ray crystallography
cognate interactions
cross-interactions
molecular insulation
antitoxin
TA systems
addiction
anti-addiction
type I toxin-antitoxin system
small protein toxin structure
Fst/Ldr family
toxin-antitoxin
M. tuberculosis
bacteria
pathogenesis
protein-protein interactions
cross-talk
protein interface
tolerance
persistence
cross-resistance
PemI/PemK
Klebsiella pneumoniae
toxin activation
antibacterial agents
bacterial persistence
Stenotrophomonas maltophilia
opportunistic pathogen
clinical origin
environmental origin
biofilm
antibiotic resistance
cell wall inhibition
nucleotide hydrolysis
uridine diphosphate-N-acetylglucosamine
n/a
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