Insulin-Like Growth Factors in Development, Cancers and Aging

Insulin-Like Growth Factors in Development, Cancers and Aging

This Special Issue of Cells on "Insulin-Like Growth Factors in Development, Cancers and Aging" provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects...

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Bibliographic Details
Other Authors: Werner, Haim (Editor)
Format: Book Chapter
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Research & information: general
Biology, life sciences
IGF-I
IGF-II
insulin
IGF-IR
IRs
tyrosine kinase receptor
GPCRs
hybrids
phosphorylation
G-proteins
β-arrestins
functional RTK/GPCR hybrid
nuclear translocation
IGF-I receptor
signaling
targeted therapeutics
IGF-Trap
IGF system
IGFBP-3
IGFBP-3R
TMEM219
anti-tumor
anti-metastatic
agonists
mAb therapy
IGF-1
IGFBP-1
older adults
longevity
health-span
age-related disease
cognitive impairment
diabetes
mitochondria
growth hormone
insulin-like growth factor-1
aging
oxidative stress
senescence
longitudinal study
IGFBP
mouse models
skeletal muscle
MSCs
myogenesis
glucose regulated protein (GRP) 94
insulin-like growth factor
obligate chaperone
hypertrophy
atrophy
cachexia
muscle regeneration
autophagy
IGF-1R
insulin receptor
IR-A
structural studies
receptor activation
n/a
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