Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances

Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances

Marine natural products are characterized by high chemical diversity, biochemical specificity, and other molecular properties that make them favorable as lead structures for drug discovery. In this field, one of the main problems is often the reduced natural availability of isolated substances, whic...

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Bibliographic Details
Other Authors: Manzo, Emiliano (Editor)
Format: Book Chapter
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Language
organic synthesis
meroterpenoids
thiazinoquinones
antiproliferative activity
G0/G1 cell-cycle arrest
cytostatic
solid tumor cell lines
alkylglycerol (AKG)
ricinoleic acid (RA)
antimicrobial activity
structure-activity relationship (SAR) studies
antibiotics (gentamicin
tetracycline
ciprofloxacin and ampicillin)
marine-inspired
breast cancer
bis-indoles
synthesis
apoptosis
carbohydrates
polysaccharides
semi-synthesis
sulfation
glycosylation
fucose
fucosylated chondroitin sulfate
marine natural product
largazole
HDAC inhibitors
modification
fluoro olefin
total synthesis
natural product
7-deazapurine nucleoside
disaccharide nucleoside
tubercidin
aureol
tetracyclic meroterpenoids
natural products synthesis
labdane scaffold
bioactive diterpenes
sclareolide
structure-activity relationships
TRPV4 channel
amides/esters
COVID-19
SARS-CoV-2
lipophilic iminosugars
polymer-supported triphenyl phosphine
cholesterol
antibacterial iminosugars
n/a
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