Marine Natural Products as Anticancer Agents

Cancer remains one of the most significant threats to human health and one of the deadliest diseases worldwide, making it crucial to develop new drugs. Over the last few decades, natural products have become one of the key drivers in the development of innovative cancer treatments. Despite drug deve...

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Další autoři:	Alves, Celso (Editor), Diederich, Marc (Editor)
Médium:	Kapitola
Vydáno:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Témata:	Medicine alga marine-derived fungus Penicillium chrysogenum polyketide hydroxyphenylacetic acid cytotoxicity flaccidoxide-13-acetate hepatocellular carcinoma invasion migration epithelial-mesenchymal transition prostate cancer astaxanthin STAT3 proliferation colony formation apoptosis Sarcophyton digitatum biscembranoid-type metabolites inflammatory factor production LPS-stimulated murine macrophage Ehlich's tumor P. purpurogenum antitumor meroterpenoids inflammation T47D BT20 pontin mutp53 cancer stem cells Oct4 Nanog siRNA secondary metabolites epigenome epigenetic signaling bioactive compounds cancer therapy marine species environment total synthesis natural product nannocystin anti-cancer gram-scale aplysinopsin analogs indole alkaloids marine source chronic myeloid leukemia BH3 mimetics n/a
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Marine Natural Products as Anticancer Agents

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