Advances in DNA Vaccines

DNA is a rapidly developing vaccine platform for cancer and infectious and non-infectious diseases. Plasmids are used as immunogens to encode proteins to be further synthesized in vaccine recipients. DNA is mainly synthetic, ensuring enhanced expression in the cells of vaccine recipients (mostly mam...

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Bibliographic Details
Other Authors:	Isaguliants, Maria (Editor), Ljungberg, Karl (Editor)
Format:	Book Chapter
Published:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:	Medicine Epidemiology & medical statistics alphaviruses layered RNA/DNA vectors DNA vaccines RNA replicons recombinant particles tumor regression protection against tumor challenges and infectious agents ebola virus disease artificial T-cell antigens DNA vaccine constructs computer design gene expression immunogenicity DNA vaccine mRNA vaccine plasmid DNA in vitro transcribed mRNA immune responses formulations Cytolytic T Lymphocytes antibodies innate immunity adjuvants vaccine delivery plasmid cytolytic perforin bicistronic HCV HIV IL-36 adjuvant DNA Zika Epstein-Barr virus latent proteins LMP2 EBNA1 LMP1 HIV-1 enhancer element circovirus influenza immunization intranasal lipid flagellin BCG vaccine rBCG HTI T-cell AIDS clinical trial therapeutic vaccine hepatitis C virus (HCV) mesenchymal stem cells (MSC) modified MSC DNA immunization nonstructural HCV proteins immune response HCV vaccine myeloid derived suppressor cells (MDSCs) n/a
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Advances in DNA Vaccines

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