The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder

The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder

Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological processes. The knowledge of the 3D structure of a protein, as well as the possible conformational transitions occurring upon interaction with dive...

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Bibliographic Details
Other Authors: Leone, Marilisa (Editor)
Format: Book Chapter
Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
Research & information: general
mass spectrometric epitope mapping
gas phase immune complex dissociation
apparent gas phase dissociation constants
apparent gas phase activation energies
ITEM-TWO
native mass spectrometry
TRIOBP
cancer
deafness
hearing loss
mental illness
schizophrenia
actin
cytoskeleton
disordered structure
protein aggregation
solid-state NMR
ELDOR-detected NMR
ATP hydrolysis
ATP analogues
DnaB helicase
ABC transporter
biopesticides
antifungal activity
insecticidal activity
mechanism of action
transgenic crops
protein folding
NMR
High Hydrostatic Pressure
ACE2
viral spike receptor-binding domain
SARS-CoV-2
transmission
bioinformatics
IDP 1
binding 2
molecular dynamics 3
MELD×MD 4
advanced sampling 5
p53 6
MDM2 7
NAD(P)H-dependent oxidoreductase
zinc-containing alcohol dehydrogenase
cofactor binding and release
interdomain cleft dynamics
molecular dynamics simulations
denatured state ensemble
protein coil library
peptides
intrinsically disordered proteins
ion-pairing interaction
side-chain length
charged amino acids
β-hairpin
peptide
Friedman's test
backbone atom coordinate variances and uncertainties
superimposition
nanobody
protein structure
immunoglobulin domain
n/a
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