The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder

Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological processes. The knowledge of the 3D structure of a protein, as well as the possible conformational transitions occurring upon interaction with dive...

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مؤلفون آخرون:	Leone, Marilisa (المحرر)
التنسيق:	فصل الكتاب
منشور في:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
الموضوعات:	Research & information: general mass spectrometric epitope mapping gas phase immune complex dissociation apparent gas phase dissociation constants apparent gas phase activation energies ITEM-TWO native mass spectrometry TRIOBP cancer deafness hearing loss mental illness schizophrenia actin cytoskeleton disordered structure protein aggregation solid-state NMR ELDOR-detected NMR ATP hydrolysis ATP analogues DnaB helicase ABC transporter biopesticides antifungal activity insecticidal activity mechanism of action transgenic crops protein folding NMR High Hydrostatic Pressure ACE2 viral spike receptor-binding domain SARS-CoV-2 transmission bioinformatics IDP 1 binding 2 molecular dynamics 3 MELD×MD 4 advanced sampling 5 p53 6 MDM2 7 NAD(P)H-dependent oxidoreductase zinc-containing alcohol dehydrogenase cofactor binding and release interdomain cleft dynamics molecular dynamics simulations denatured state ensemble protein coil library peptides intrinsically disordered proteins ion-pairing interaction side-chain length charged amino acids β-hairpin peptide Friedman's test backbone atom coordinate variances and uncertainties superimposition nanobody protein structure immunoglobulin domain n/a
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DOAB: description of the publication

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The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder

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3rd Floor Main Library

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