Colorectal Cancer : From Pathophysiology to Novel Therapeutic Approaches

Colorectal Cancer : From Pathophysiology to Novel Therapeutic Approaches

Colorectal cancer is one of the most common malignancies worldwide, and the pathogenesis of this neoplasm is probably one of the most studied. The knowledge obtained over time has led to the development of screening and early diagnosis systems, allowing a significant reduction in the incidence of th...

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Bibliographic Details
Other Authors: Barresi, Valeria (Editor)
Format: Book Chapter
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Medicine
MSH2 3'UTR variant
hereditary colon cancer
Lynch syndrome
MSH2 protein
over expression MSH2
MMR gene
MMR complex deficiency
MSH2 unclassified variants
liquid biopsy
colorectal cancer
biomarkers
circulating tumor cells
circulating tumor DNA
genomic alterations
metastasis
tumor heterogeneity
tumor evolution
ADAM17
colorectal cancer (CRC)
TNFα
IL-6R
AREG
shedding
regularized optimization
Cox regression
survival analysis
TCGA data
RNA-seq data
gut microbiota
colorectal adenoma
polyps
bacteria
monoclonal antibody
therapeutic target
therapy
colon cancer
poorly differentiated clusters
prognostic factors
inflammatory markers
histopathological markers
immune system
colorectal surgery
nanofibrous materials
anastomotic leakage
intestinal anastomosis
anastomotic patch
polycaprolactone
electrospinning
experiment
peritoneal adhesions
CRC
CTC
ctDNA
mi-RNA
nc-RNA
differentially expressed genes
cancer stem cells
qPCR
chemoresistance
TRIM8
miR-17-5p
PDX
patient-derived xenograft
omega-3 fatty acids
n/a
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