Genetics of Alzheimer's Disease

Genetics of Alzheimer's Disease

This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future A...

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Bibliographic Details
Other Authors: Ibanez, Laura (Editor), Miller, Justin (Editor)
Format: Book Chapter
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Medicine
Neurosciences
Alzheimer disease
expression quantitative trait loci (eQTL)
rare variants
set-based eQTL
SKAT-O
pathways
immune system
inflammation
ROSMAP
ADNI
complement
complement receptor 1
clusterin
late-onset Alzheimer's disease
genetics
neuroinflammation
Alzheimer's disease
cytokines and growth factors
genome-wide association study (GWAS)
Polygenic Risk Score (PRS)-based analysis
TOMM40 gene
RNA transcription
pseudogene
mitochondrial dysfunction
ITIM
ITAM
SIGLEC14
SIGLEC5
copy number variation
CNV
GWAS
long non-coding RNA
biomarkers
peripheral system
amyloid β
tau
APOE
TREM2
OMICS
therapeutics
pairwise feature correlation
feature reduction
machine learning
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