The Role of Complement in Cancer Immunotherapy

The dual role of complement in both cancer development and treatment has been investigated extensively and is characterized by a substantial literature that documents the conditions in which complement can either enhance tumor growth or promote the killing of malignant cells. Indeed, there are now n...

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Outros autores:	Taylor, Ronald P. (Editor)
Formato:	Capítulo de libro
Publicado:	Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:	Medicine complement therapeutic monoclonal antibodies (mAbs) Ca2+ fluorescence microscopy gC1qR breast cancer xenotransplant model complement system cancer immune infiltrate tumor microenvironment tumor growth anaphylatoxins antibody dependent cellular cytotoxicity phagocytosis complement receptors CD46 membrane cofactor protein (MCP) cancer therapeutics measles virus adenovirus antibody-drug conjugates immunity myeloid cells therapeutics antibody therapy cluster of differentiation 19 (CD19) CD19 Fc fragment crystallizable (Fc) Fc engineering complement-dependent cytotoxicity (CDC) antibody-dependent cell-mediated cytotoxicity (ADCC) angiogenesis ocular pathology cytotoxicity monoclonal antibody B-cell lymphoma chronic lymphocytic leukemia (CLL) complement C5a complement C3a mammary carcinoma immunoregulation tumor infiltrating leukocytes n/a
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Número de Clasificación:	A1234.567
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The Role of Complement in Cancer Immunotherapy

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