The Role of Complement in Cancer Immunotherapy

The Role of Complement in Cancer Immunotherapy

The dual role of complement in both cancer development and treatment has been investigated extensively and is characterized by a substantial literature that documents the conditions in which complement can either enhance tumor growth or promote the killing of malignant cells. Indeed, there are now n...

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Dades bibliogràfiques
Altres autors: Taylor, Ronald P. (Editor)
Format: Capítol de llibre
Publicat: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Matèries:
Medicine
complement
therapeutic monoclonal antibodies (mAbs)
Ca2+
fluorescence microscopy
gC1qR
breast cancer
xenotransplant model
complement system
cancer
immune infiltrate
tumor microenvironment
tumor growth
anaphylatoxins
antibody dependent cellular cytotoxicity
phagocytosis
complement receptors
CD46
membrane cofactor protein (MCP)
cancer therapeutics
measles virus
adenovirus
antibody-drug conjugates
immunity
myeloid cells
therapeutics
antibody therapy
cluster of differentiation 19 (CD19)
CD19
Fc fragment crystallizable (Fc)
Fc engineering
complement-dependent cytotoxicity (CDC)
antibody-dependent cell-mediated cytotoxicity (ADCC)
angiogenesis
ocular pathology
cytotoxicity
monoclonal antibody
B-cell lymphoma
chronic lymphocytic leukemia (CLL)
complement C5a
complement C3a
mammary carcinoma
immunoregulation
tumor infiltrating leukocytes
n/a
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